Scandic Journal of Advanced Research and Reviews
ISSN 2703-965X

International Journal with High Impact Factor for fast publication of Research and Review articles

Nedre prinsdal vei 143, 1263 Oslo, Norway

Clinical diagnostic significance of tumor suppressor gene methylation in oral mucosal lesions

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Vol. 2, Issue 6, MAY 2022

Submission : up to 29th April

Editorial decision: 48 hrs

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Dr Shehzad Khan, Dr Saba Kaynat

Research Article

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Multiple genetic and epigenetic changes in critical regulatory genes have a role in the development of oral cancer. When genes are silenced by abnormally high levels of promoter hypermethylation, they have the potential to serve as biomarkers for early diagnosis, tumor molecular subtyping, prognosis and treatment monitoring. Different liquid biopsies have been found to have abnormal DNA methylation, which may be a viable alternative to solid biopsies. Noninvasive mouth cancer screening and early diagnosis could benefit from saliva testing for methylation genes. Gene promoter hypermethylation in saliva is examined here.


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