The polystyrene is the specific kind of plastics based upon petroleum which is composed of
monomers of vinyl benzene (styrene). Regardless of the attraction of polystyrene, multiple
organizations and municipalities are enduring an emerging challenge during disposal of
polystyrene products and packaging. It is appraised that the products of polystyrene accounts for
not more than 1% of the overall burden of landfill resources. It could be a greater health threat for
humans also who are on the topmost level of food chain and farsighted styrene monomers of the
plastics used in engineering polystyrene has been categorized as a potential humanoid carcinogen by the International Agency for Research on Cancer (IARC) and the US National Institutes of
Health (NIH). As a few researchers have been published on the degradation of polystyrene plastic
but the key point addressed in this review is the recognition of microbial and fungal enzymes which
are known at present to be involved in polystyrene monomer plastic degradation. The major
bacterial and fungal enzymes involved within the degradation reaction of vinyl side chain include
styrene monooxygenase, styrene oxide isomerase, styrene monooxygenase, flavin adenine
dinucleotide (FAD) reductase, styrene isomerase and phenyl acetaldehyde dehydrogenase.
Omics”-based approaches revitalized the study of PAH catabolism by permitting for an integrative
assessment of the biochemical mechanism in charge to degrade PAH including polystyrene on the
polluted locations. The applications of such enzymes in procedures that would permit the
degradation of polystyrene plastics contaminating niches is a dare for future cohorts of
microbiology experts