Thyroid cancer the most serious endocrine malignancy mostly diagnosed in young people and more commonly in females. The managing of the pregnant female with thyroid cancer is inescapably linked with substantial concern for both clinician and patient principally for any recommended treatment. The aim of this study was to analyze unanimously diagnostic and surgical outcomes in the patients with thyroid cancer treated with minimally invasive techniques. 13 patients were suspected thyroid cancer were treated at the at the Department of Surgery of Liaquat University of Medical & Health Sciences, Jamshoro, Sindh, Pakistan. The average age of the pregnant females at the time of diagnostics was 35 years (ranges 31-39 years). In three patients, the thyroid cancer was recognized during first trimester, in six patients during second trimester and in the four patients during third trimester of pregnancies. The diagnostics of all tumors were made by expert pathologists by means of recognized criteria. After surgical procedure, the treatment of thyroxine accomplished to the patients in the sufficient doses for suppressing the level of thyrotrophin (TSH). Average follow-up was 6.5 years (4–9 years). In total, 12 of 13 patients are alive and completely cured with normal level of serum thyroglobulin. Seven babies have been born then among eight of those patients. The excellent outcomes expected for both follicular or papillary differentiated thyroid cancer in young cases. Thyroid surgery during pregnancy is verified to be secure though it is linked with enlarged fatal loss in more widely surgery such as neck dissection.